This issue of Eurohealth provides interesting oversight of the key issues surrounding the digitalization of health systems and how together, we can leverage the benefits of digital health.

Guest editorial; Governance and leadership for the future of digital health - Charting the future of digital health systems in the WHO European Region; Next generation digital health systems - Building and maintaining public trust to support the secondary use of personal health data, Developing effective policy to support artificial intelligence in health and care; Working together to create health services of the future - Digital health driven prevention as a clinical reality (Israel); National success in digital health - ePrescription success in Estonia, Achieving better health and well-being via the Danish eHealth portal, The future development of digital health in Kazakhstan; and Eurohealth Monitor.

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