Biological risk assessment at workplaces is not easy because of the lack of a standard for biocontaminants measurement. INAIL's Technical Advisory Risk Assessment and Prevention (CONTARP) developed guidelines on microbiological monitoring in workplaces, in order to adopt homogeneous methodologies of airborne biocontaminants sampling and samples analysis. CONTARP and DCOD (Directorate for Digital Organization) developed a software programme, whose database contains data about environmental microbiological monitoring in companies. Data set includes results of sampling and analysis of microorganisms in the air and on the surfaces of workplaces, and any other tool of interest used at work, to measure microbiological contamination. The aim was to make available a large quantity of information and data collected according to homogeneous methodologies, useful to assess biological risk at work and to support prevention. Data included in the database are homogeneous and meet the criteria of standardization. The framework was validated by other institutions who deal with health and safety at work, such as the Local Health Authority and Regional Agency For Environmental Protection (ARPA), for data sharing in order to create a network to prevent occupational biological risks.