Jakarta State University (2023) This study aims to examine the effect of Transformational Leadership and Organizational Culture on Good Corporate Governance at the head office of the Health Social Security Administration (BPJS Kesehatan). The methods of this research are quantitative methods and data processing using Structural Equation Modeling (SEM PLS) using the SmartPLS 3.0 software program. And the respondents in this research are BPJS Health employees with a total of 156 participants. Which includes 55 male, 101 female, among them there are 70 participants by the age of 30 years old, and 86 participants over 30 years old. The results of this study show that, (1) there is a positive direct influence of transformational leadership on good corporate governance, and (2) there is a direct positive influence of organizational culture on good corporate governance.