Due to growth of heath costs, especially cost of medicine and in order to promote quality of health services, it is highly necessary to consider solutions such as strategic purchasing of health services aiming at cost control and shortening fiscal burden as well as preventing medical errors. In line with high level targets of the ISSO and facilitation and expedition of the processes, increasing system efficiency and meet the e-government goals, planning and implementing the “electronic prescription” scheme came on the agenda. This widespread green scheme not only leaded to restore tons of paper but also caused considerable changes in the process of medicine prescription, easy monitoring service provision, less time consuming for contractors and reduction and total deletion of medical errors. Because of being the first purchaser as well as second provider of medical and health services, and as a pioneer in promoting technical and scientific aspects of services in Iran, the ISSO has delivered the e-prescription and is now the first organization to provide the beneficiaries, whom are more than 50 million audiences with this kind of services.